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dc.contributor.authorAlansare, Abdullah Bandar
dc.contributor.authorBates, Lauren C
dc.contributor.authorStoner, Lee
dc.contributor.authorKline, Christopher E
dc.contributor.authorNagle, Elizabeth
dc.contributor.authorJennings, J Richard
dc.contributor.authorHanson, Erik D
dc.contributor.authorFaghy, Mark A
dc.contributor.authorGibbs, Bethany Barone
dc.date.accessioned2021-09-14T09:46:03Z
dc.date.available2021-09-14T09:46:03Z
dc.date.issued2021-08-12
dc.identifier.citationAlansare, A.B., Bates, L.C., Stoner, L., Kline, C.E., Nagle, E., Jennings, J.R., Hanson, E.D., Faghy, M.A. and Gibbs, B.B., (2021). 'Associations of Sedentary Time with Heart Rate and Heart Rate Variability in Adults: A Systematic Review and Meta-Analysis of Observational Studies'. International Journal of Environmental Research and Public Health, 18(16), pp. 1-17.en_US
dc.identifier.pmid34444256
dc.identifier.doi10.3390/ijerph18168508
dc.identifier.urihttp://hdl.handle.net/10545/625992
dc.description.abstractTo evaluate if sedentary time (ST) is associated with heart rate (HR) and variability (HRV) in adults we systematically searched PubMed and Google Scholar through June 2020. Inclusion criteria were observational design, humans, adults, English language, ST as the exposure, resting HR/HRV as the outcome, and (meta-analysis only) availability of the quantitative association with variability. After qualitative synthesis, meta-analysis used inverse variance heterogeneity models to estimate pooled associations. Thirteen and eight articles met the criteria for the systematic review and meta-analysis, respectively. All studies were cross-sectional and few used gold standard ST or HRV assessment methodology. The qualitative synthesis suggested no associations between ST and HR/HRV. The meta-analysis found a significant association between ST and HR (β = 0.24 bpm per hour ST; CI: 0.10, 0.37) that was stronger in males (β = 0.36 bpm per hour ST; CI: 0.19, 0.53). Pooled associations between ST and HRV indices were non-significant (p > 0.05). Substantial heterogeneity was detected. The limited available evidence suggests an unfavorable but not clinically meaningful association between ST and HR, but no association with HRV. Future longitudinal studies assessing ST with thigh-based monitoring and HRV with electrocardiogram are neededen_US
dc.description.sponsorshipN/Aen_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.relation.urlhttps://www.mdpi.com/1660-4601/18/16/8508en_US
dc.rightsAttribution-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nd/4.0/*
dc.subjectautonomic regulationen_US
dc.subjectheart rate variabilityen_US
dc.subjectlifestyle behaviorsen_US
dc.subjectsedentary timeen_US
dc.subjectvagal activityen_US
dc.titleAssociations of Sedentary Time with Heart Rate and Heart Rate Variability in Adults: A Systematic Review and Meta-Analysis of Observational Studies.en_US
dc.typeArticleen_US
dc.identifier.eissn1660-4601
dc.contributor.departmentKing Saud University, Saudi Arabiaen_US
dc.contributor.departmentUniversity of North Carolina, Chapel Hill, NCen_US
dc.contributor.departmentUniversity of Pittsburgh, PA, USAen_US
dc.contributor.departmentUniversity of Derbyen_US
dc.identifier.journalInternational Journal of Environmental Research and Public Healthen_US
dc.source.journaltitleInternational journal of environmental research and public health
dc.source.volume18
dc.source.issue16
dcterms.dateAccepted2021-08-09
refterms.dateFOA2021-09-14T09:46:04Z
dc.author.detail782098en_US
dc.source.countrySwitzerland


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